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Sleep – Genetic Predispositions & Risks

Upload your raw DNA data and learn about your genetic risks & predispositions!

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Insomnia (source: Lane, 2016)

Insomnia, characterized by difficulty falling asleep or staying asleep, is one of the most common sleeping disorders. This study gathered genetic data from 113,006 individuals of European ancestry and identified novel genetic variants that are linked to insomnia.

Snoring (source: Campos, 2020)

Snoring may disrupt your or your partner’s sleep. It is incredibly common and affects more men (35-45%) than women (15-28%). This study utilized genomes of ~400,000 individuals of European ancestry from the UK Biobank to understand the genetic basis of snoring. The researchers discovered 42 genetic regions associated with snoring.

Daytime sleepiness (source: Wang, 2019)

More than 1 in 10 people are affected by excessive daytime sleepiness, which can be a broader symptom of many sleep-related disorders like sleep apnea and narcolepsy. This analysis identified 42 novel genetic variants associated with excessive daytime sleepiness.

Restless leg syndrome (source: Winkelmann, 2011)

Restless leg syndrome causes uncomfortable sensations in the legs and irresistible urges to move them. This most often affects the patient at night, making it difficult to get a good night’s sleep. Restless leg syndrome is associated with variants near the MEIS1 gene and in the TOX3 gene.

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