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Skin – Genetic Predispositions & Risks

Upload your raw DNA data and learn about your genetic risks & predispositions!

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Vitiligo (source: Jin, 2017)

Vitiligo is a rare disease characterized by the destruction of melanocytes by the body’s own immune system. This causes patches of skin to lose their color. To better understand the genetic susceptibility to vitiligo, this genome-wide association study examined the genomes of over 44,000 individuals of European ancestry. The study identified 50 genetic variants of which 23 are newly discovered.

Acne (source: Navarini, 2014)

Acne is an inflammatory disease of the skin in which hair follicles become clogged with oil and dead skin cells. Acne is about 80% heritable. This genome-wide association study included 1,893 patients with severe acne and 5,132 healthy individuals from the United Kingdom.

Psoriasis (source: Tsoi, 2015)

In an effort to better understand genetic variants that lead to an increased risk of developing psoriasis, this study examined 10,740 individuals of European ancestry. This study identified 6 genetic variants that may increase the risk of psoriasis.

Alopecia areata (source: Petukhova, 2010)

Identification of 16 genomic regions associated with alopecia areata, an autoimmune disease that causes hair loss.

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